Our Practices and Services

Regenerative spine and musculoskeletal medicine (RSM Medicine) is the choice for diagnosis and treatment of acute and chronic joint, muscle, nerve and spine pain disorders. We specialize in all aspects of musculoskeletal care, including the diagnosis and treatment of spine, shoulder, elbow, hip, knee, arthritis, muscle, congenital disorders, and work-related injuries.

RSM Medicine offers nonsurgical solutions for your musculoskeletal, nerve and spinal issues, with an emphasis on integrative, holistic and regenerative medicine. Our team provides Central New York’s families with comprehensive care using innovative medical technology in a timely and expert fashion.

RSM medicine is also the home of Renaissance Medicine, acupuncture & integrative medicine.


Dr. Renée S. Melfi, M.D., FAAPMR, DABPM, ABIHM

Dr. Renée S. Melfi, graduated from St. George’s University School of Medicine and went on to complete her residency in Physical Medicine and Rehabilitation at the prestigious Baylor College of Medicine. While at Baylor College of Medicine, she served as Chief Resident and was awarded the Oliver R. Smith, M.D.Read more


Rachel Bossi, PA-C

Rachel Bossi, PA-C joined the RSM family in 2015. Rachel is a graduate of Bellarmine University, (Louisville, KY) where she attained a Bachelor’s Degree in Biology with a Chemistry minor. Prior to attending PA school, Rachel completed three years of clinical experience. She worked as an EMT in Kentucky forRead more


Melissa Saxton MS FNP-C

Melissa Saxton MS FNP-C, graduated SUNY Upstate as a Nurse Practitioner in 2013. She is a graduate of Clarkson University with a Bachelor’s Degree in Bio-Molecular Science, and has an Associate’s Degree in Nursing. She has worked in Pain Management and Rehabilitation for 3 years. She brings experience as anRead more

See what we can do for you!

"Jessica was so very helpful in getting me in to see Dr. Melfi along with her compassionate understanding of my need for a Rx for my lidoderm patches even though I had not been here for some time. Even though I need an appointment first, she was so sweet about it all."

Happy Patient!

"Since 2005 Dr. Renee Melfi & staff have coordinated an intensive treatment plan for the disabling conditions of my fractured neck sustained during sever domestic violence. I think their accurate diagnoses are only matched by their sincere interest in me and how I am best able to manage chronic pain. I thoroughly enjoy the opportunities the provide for me to learn about my own mind/body connection and how I can build on my capabilities despite my challenges."

Terri E.
Happy Patient!